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Phenotypes Associated with This Genotype
Genotype
MGI:4461313
Allelic
Composition
Hoxa3tm2Nrm/Hoxa3tm3.1Nrm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background
involves: C3H * C57BL/6 * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Hoxa3tm2Nrm mutation (0 available); any Hoxa3 mutation (26 available)
Hoxa3tm3.1Nrm mutation (0 available); any Hoxa3 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• at E15.5, parathyroids are ectopically attached to the thymus unlike in wild-type mice
• however, parathyroid morphology is normal
• at E15.5, thymic lobes are absent from their normal position and are ectopically attached to the pharynx unlike in wild-type mice
• however, thymic lobe morphology is normal

immune system
• at E15.5, thymic lobes are absent from their normal position and are ectopically attached to the pharynx unlike in wild-type mice
• however, thymic lobe morphology is normal

hematopoietic system
• at E15.5, thymic lobes are absent from their normal position and are ectopically attached to the pharynx unlike in wild-type mice
• however, thymic lobe morphology is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory