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Phenotypes Associated with This Genotype
Genotype
MGI:4461139
Allelic
Composition
Tg(Tnf)6074Gkl/0
Tnfrsf1btm1Mwm/Tnfrsf1btm1Mwm
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tnf)6074Gkl mutation (1 available)
Tnfrsf1btm1Mwm mutation (2 available); any Tnfrsf1b mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in 4 week old mice
• in 4 week old mice
• cerebellum myelin vacuolation in 4 week old mice

immune system
• in 4 week old mice

cellular
• in 4 week old mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
multiple sclerosis DOID:2377 OMIM:612594
OMIM:612595
OMIM:612596
J:106592


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/03/2022
MGI 6.21
The Jackson Laboratory