Mouse Genome Informatics
cx
    Tg(Gfap-TNF*)K21Gkl/0
Tnfrsf1atm1Blt/Tnfrsf1a+

involves: 129P2/OlaHsd * C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• neurological symptoms by the sixth month of age, delayed compared to Tg alone
• at 6 months CNS shows symmetrical, focal demyelinated plaques at the capsula interna and in the spinal cord

Mouse Models of Human Disease
OMIM IDRef(s)
Multiple Sclerosis, Susceptibility To; MS 126200 J:106592