Phenotypes Associated with This Genotype

Genotype
MGI:4460230

• Allelic Composition: Il10^tm1Cgn/Il10^tm1Cgn
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:84100 )

• lower body weight than controls

digestive/alimentary system

colitis ( J:84100 )

• increased lymphocytes in the lamina propria

• inflamatory cells in the mucosa

• epithelial hyperplasia

• reduced mucin producing goblet cells

immune system

colitis ( J:84100 )

• increased lymphocytes in the lamina propria

• inflamatory cells in the mucosa

• epithelial hyperplasia

• reduced mucin producing goblet cells