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Phenotypes Associated with This Genotype
Genotype
MGI:4454433
Allelic
Composition		 a/a
Myo5ad/Myo5ad
Genetic
Background		 involves: DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Myo5ad mutation (104 available); any Myo5a mutation (266 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal hair follicle melanin granule distribution ( J:5346 )
• mice have clumped granules in the hair and skin
abnormal choroid melanin granule morphology ( J:5346 )
• granules tend to clump in the choroid but not in the retina

vision/eye
abnormal choroid melanin granule morphology ( J:5346 )
• granules tend to clump in the choroid but not in the retina

integument
abnormal hair follicle melanin granule distribution ( J:5346 )
• mice have clumped granules in the hair and skin

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory