About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4453458
Allelic
Composition		 Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Tbx1tm3.1Bld/Tbx1tm6(cre)Bld
Genetic
Background		 involves: 129S4/SvJaeSor * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1095 available)
Tbx1tm3.1Bld mutation (1 available); any Tbx1 mutation (36 available)
Tbx1tm6(cre)Bld mutation (1 available); any Tbx1 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymphatic vessel morphology ( J:159824 )
• abnormal lymphatic vessels fail to extend into distal mesentery unlike in wild-type mice
• between E15.5 and E16.5, lymphatic vessels are almost completely lost unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory