About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4453314
Allelic
Composition
A/?
Lystbg/Lystbg
Tyrp1+/?
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (80 available); any a mutation (468 available)
Lystbg mutation (6 available); any Lyst mutation (227 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• on an agouti black (A-B-) background, mice exhibit reduced ear pigmentation relative to wild-type controls
• on an agouti black (A-B-) background, mice exhibit a lighter coat color than wild-type controls, particularly at the base of the hairs
• basal dilution is first noted at ~15 days of age, is somewhat variable, and tends to become darker in older mice
• on an agouti black (A-B-) background, mutant dorsal hairs have a yellow subterminal band, a dark grey middle portion, and usually a very light grey base
• basal dilution is first noted at ~15 days of age, is somewhat variable, and tends to become darker in older mice
• on an agouti black (A-B-) background, mice exhibit reduced tail pigmentation relative to wild-type controls
• on an agouti black (A-B-) background, the eye pigmentation of mice is only slight at birth but varies from ruby to almost black in adults

vision/eye
• on an agouti black (A-B-) background, the eye pigmentation of mice is only slight at birth but varies from ruby to almost black in adults

limbs/digits/tail
• on an agouti black (A-B-) background, mice exhibit reduced tail pigmentation relative to wild-type controls

craniofacial
• on an agouti black (A-B-) background, mice exhibit reduced ear pigmentation relative to wild-type controls

hearing/vestibular/ear
• on an agouti black (A-B-) background, mice exhibit reduced ear pigmentation relative to wild-type controls

integument
• on an agouti black (A-B-) background, mice exhibit reduced ear pigmentation relative to wild-type controls
• on an agouti black (A-B-) background, mice exhibit a lighter coat color than wild-type controls, particularly at the base of the hairs
• basal dilution is first noted at ~15 days of age, is somewhat variable, and tends to become darker in older mice
• on an agouti black (A-B-) background, mutant dorsal hairs have a yellow subterminal band, a dark grey middle portion, and usually a very light grey base
• basal dilution is first noted at ~15 days of age, is somewhat variable, and tends to become darker in older mice
• on an agouti black (A-B-) background, mice exhibit reduced tail pigmentation relative to wild-type controls

growth/size/body
• on an agouti black (A-B-) background, mice exhibit reduced ear pigmentation relative to wild-type controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/30/2025
MGI 6.24
The Jackson Laboratory