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Phenotypes Associated with This Genotype
Genotype
MGI:4442996
Allelic
Composition		 Dact1tm1.1Bnrc/Dact1tm1.2Bnrc
Emx1tm1(cre)Krj/Emx1+
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dact1tm1.1Bnrc mutation (0 available); any Dact1 mutation (21 available)
Dact1tm1.2Bnrc mutation (1 available); any Dact1 mutation (21 available)
Emx1tm1(cre)Krj mutation (2 available); any Emx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:159217 )
N
• mice exhibit normal cellular organization and regional anatomy of the brain
abnormal dendritic spine morphology ( J:159217 )
• cultured hippocampal neurons exhibit reduced dendritic spine density, spine length, and spine head width compared with wild-type neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory