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Phenotypes Associated with This Genotype
Genotype
MGI:4441390
Allelic
Composition		 Prox1tm1Gco/Prox1tm5(GFP/cre)Gco
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prox1tm1Gco mutation (0 available); any Prox1 mutation (50 available)
Prox1tm5(GFP/cre)Gco mutation (0 available); any Prox1 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased lymphatic vessel endothelial cell number ( J:158959 )
• only a few scattered lymphatic endothelial cells (LECs) are found at E11.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory