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Phenotypes Associated with This Genotype
Genotype
MGI:4441337
Allelic
Composition		 Robo3tm1Matl/Robo3tm1Matl
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo3tm1Matl mutation (1 available); any Robo3 mutation (76 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Reduced internuclear commissure in Robo3tm1.1Ache/Robo3tm1.1Ache Egr2tm2(cre)Pch/Egr2+ and Robo3tm1Matl/Robo3tm1Matl mice

nervous system
abnormal brain commissure morphology ( J:158918 )
• at E14 and in newborns, virtually no axons are found to cross the midline at the level of the abducens nuclei

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory