Phenotypes for Bhlhe22 H2az2 MGI:4440902 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Bhlhe22^tm2.1Meg/Bhlhe22^tm2.1Meg H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Genetic Background	involves: 129/Sv * C57BL/6J * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bhlhe22^tm2.1Meg mutation (0 available); any Bhlhe22 mutation (12 available)
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

excessive scratching ( J:158273 )

• mice show excessive scratching in response to pruritic agent compound 48/80

abnormal chemical nociception ( J:158273 )

• mice show excessive scratching in response to pruritic agent compound 48/80

integument

skin lesions ( J:158273 )

• animals display self-inflicted skin lesions, identical in frequency, location, and severity to those observed in Bhlhe22^tm1Meg homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24