About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4438065
Allelic
Composition
Fbn2mz/Fbn2mz
Genetic
Background
involves: BALB/cAnNCrl * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbn2mz mutation (0 available); any Fbn2 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Muscle weakness in Fbn2mz/Fbn2mz mice

muscle
• in the soleus muscle (J:157998)
• in the soleus muscle (J:157998)
• at 4 months, peak isometric tetanic force is higher than in wild-type muscle cells (J:157998)
• however, peak isometric stress is normal (J:157998)
• at 4 months, peak isometric tetanic force is higher than in wild-type muscle cells (J:157998)
• however, peak isometric stress is normal (J:157998)
• generalized (J:157998)
• generalized (J:157998)

behavior/neurological
• mice exhibit poor performance in the MoRAG test for measuring grasping and retrieval of food pellets compared with wild-type mice (J:157998)
• mice exhibit poor performance in the MoRAG test for measuring grasping and retrieval of food pellets compared with wild-type mice (J:157998)
• in the grip strength and wire maneuver tests (J:157998)
• in the grip strength and wire maneuver tests (J:157998)

limbs/digits/tail
• with two or more adjacent toes on the hind limb paw (J:157998)
• with two or more adjacent toes on the hind limb paw (J:157998)

growth/size/body

skeleton

Mouse Models of Human Disease
OMIM ID Ref(s)
Arthrogryposis, Distal, Type 9; DA9 121050 J:157998


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory