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Phenotypes Associated with This Genotype
Genotype
MGI:4437854
Allelic
Composition		 Jag1tm1Jlew/Jag1tm1Jlew
Tg(Tie1-cre)9Ref/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jag1tm1Jlew mutation (0 available); any Jag1 mutation (78 available)
Tg(Tie1-cre)9Ref mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
fetal growth retardation ( J:157345 )
• embryos show growth retardation compared to littermate controls at E17.5

cardiovascular system
abnormal vascular branching morphogenesis ( J:157345 )
• at E17.5, skin in the head region shows decreased branching and capillary density compared to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory