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Phenotypes Associated with This Genotype
Genotype
MGI:4437229
Allelic
Composition		 En1tm7(cre/ESR1)Alj/0
Fgf8tm1.3Mrt/Fgf8tm2.1Jyhl
Gt(ROSA)26Sortm1Sor/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1tm7(cre/ESR1)Alj mutation (1 available); any En1 mutation (34 available)
Fgf8tm1.3Mrt mutation (1 available); any Fgf8 mutation (25 available)
Fgf8tm2.1Jyhl mutation (0 available); any Fgf8 mutation (25 available)
Gt(ROSA)26Sortm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1084 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
growth/size/body region phenotype ( J:156717 )
N
• unlike mice homozygous for Fgf8tm2.1Jyhl, mice are normal in size

nervous system
nervous system phenotype ( J:156717 )
N
• unlike mice homozygous for Fgf8tm2.1Jyhl, the size of the midbrain and cerebellum are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory