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Phenotypes Associated with This Genotype
Genotype
MGI:4436917
Allelic
Composition
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Neurog3-cre/Esr1*)1Dam/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Notch1)Dam mutation (1 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Neurog3-cre/Esr1*)1Dam mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• unable to recover any viable embryos after E13.5

endocrine/exocrine glands
• pancreas shows absence of glucagon+ alpha cells at E13.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory