Mouse Genome Informatics
hm
    Npc1m1N/Npc1m1N
B6.C-Npc1m1N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system

hematopoietic system

homeostasis/metabolism
• mice exhibit an increase in unestrified cholesterol in the cerebellum compared with wild-type mice

cellular
• mice exhibit proliferation of foamy cells in the liver unlike wild-type mice

immune system

Mouse Models of Human Disease
OMIM IDRef(s)
Niemann-Pick Disease, Type C1; NPC1 257220 J:157113