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Phenotypes Associated with This Genotype
Genotype
MGI:4431260
Allelic
Composition		 Ephb2tm4.1Jf/Ephb2tm4.1Jf
Ephb3tm1Kln/Ephb3tm1Kln
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ephb2tm4.1Jf mutation (0 available); any Ephb2 mutation (66 available)
Ephb3tm1Kln mutation (1 available); any Ephb3 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
digestive/alimentary phenotype ( J:157019 )
N
• unlike in Ephb2tm2Paw Ephb3tm1Kln double mutants, Paneth cell positioning is normal
abnormal digestive system physiology ( J:157019 )
• reduction in the number of mitotic cells in intestinal crypts was indistinguishable from unlike in Ephb2tm3.1Jf Ephb3tm1Kln double mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory