Phenotypes Associated with This Genotype

Genotype
MGI:4431231

• Allelic Composition: Gt(ROSA)26Sor^{tm1(RARA*)Clmd}/Gt(ROSA)26Sor^{tm1(RARA*)Clmd}; Tg(Hoxb7-cre)13Amc/0; Tg(Hoxb7-EGFP)33Cos/0
• Genetic Background: involves: 129/SvEv * C57BL/6 * CBA * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

renal hypoplasia ( J:157254 )

• severe renal hypoplasia with reduced branching at E14

absent kidney ( J:157254 )

• renal agenesis at E14

impaired branching involved in ureteric bud morphogenesis ( J:157254 )

• barely begin to branch at E11

• severe renal hypoplasia with reduced branching at E14

small ureteric bud ( J:157254 )

• smaller ureteric bud at E10.5 than in normal embryos