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Phenotypes Associated with This Genotype
Genotype
MGI:4431229
Allelic
Composition		 Gt(ROSA)26Sortm1(RARA*)Clmd/Gt(ROSA)26Sor+
Tg(Hoxb7-cre)13Amc/0
Tg(Hoxb7-EGFP)33Cos/0
Genetic
Background		 involves: 129/SvEv * C57BL/6 * CBA * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(RARA*)Clmd mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Hoxb7-cre)13Amc mutation (2 available)
Tg(Hoxb7-EGFP)33Cos mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal hypoplasia ( J:157254 )
• renal hypoplasia with a 50-80% reduction in branch numbers at E14
impaired branching involved in ureteric bud morphogenesis ( J:157254 )
• 50-80% reduction in branch numbers at E14

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory