Phenotypes for Gt(ROSA)26Sor Tg(Hoxb7-cre)13Amc MGI:4431228 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(RARA)Clmd}/Gt(ROSA)26Sor^{tm1(RARA)Clmd} Tg(Hoxb7-cre)13Amc/0
Genetic Background	involves: 129/SvEv * C57BL/6 * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(RARA*)Clmd} mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Hoxb7-cre)13Amc mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

abnormal kidney development ( J:157254 )

• few ureteric bud branches or nephrons and severe patterning abnormalities at E14

renal hypoplasia ( J:157254 )

• at E14 the kidneys are greatly reduced in size than normal

impaired branching involved in ureteric bud morphogenesis ( J:157254 )

• few ureteric bud branches at E14

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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