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Phenotypes Associated with This Genotype
Genotype
MGI:4431166
Allelic
Composition		 Artm1Jdz/Y
Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Artm1Jdz mutation (1 available); any Ar mutation (23 available)
Plekha5Tg(AMH-cre)1Flor mutation (1 available); any Plekha5 mutation (109 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
small seminiferous tubules ( J:157337 )
• seminiferous tubules with smaller diameters are observed
decreased testis weight ( J:157337 )
• testis weights at 3 weeks are significantly lower (15.9 mg) than control males (24.9-27 mg)
arrest of spermatogenesis ( J:157337 )
• spermatogenic arrest predominantly at meiotic stage with no elongated spermatids is observed at 9 weeks

endocrine/exocrine glands
small seminiferous tubules ( J:157337 )
• seminiferous tubules with smaller diameters are observed
decreased testis weight ( J:157337 )
• testis weights at 3 weeks are significantly lower (15.9 mg) than control males (24.9-27 mg)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory