Analysis Tools
growth/size/body
 N |
• total body weights of males are equivalent to wild-type males
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reproductive system
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• tubules with smaller diameters are observed at 9 weeks
• at 9 weeks total Sertoli cell numbers are same as in controls
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• at 9 weeks, interstitial Leydig cells display hypertrophy and accumulation of lipid droplets
• adult Leydig cells are present in testes at 9 weeks
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• Leydig cells display hypertrophy at 9 weeks
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• at 5 or 10 days, testis weights are normal, but testis weights at 3 weeks are significantly lower (15.9 mg) than control males (24.9-27 mg)
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• spermatogenic arrest predominantly at meiotic stage with no elongated spermatids is observed at 9 weeks
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endocrine/exocrine glands
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• tubules with smaller diameters are observed at 9 weeks
• at 9 weeks total Sertoli cell numbers are same as in controls
|
|
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• at 9 weeks, interstitial Leydig cells display hypertrophy and accumulation of lipid droplets
• adult Leydig cells are present in testes at 9 weeks
|
|
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• Leydig cells display hypertrophy at 9 weeks
|
|
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• at 5 or 10 days, testis weights are normal, but testis weights at 3 weeks are significantly lower (15.9 mg) than control males (24.9-27 mg)
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