Phenotypes Associated with This Genotype

Genotype
MGI:4430928

• Allelic Composition: Cd79b^m1Ghost/Cd79b^m1Ghost
• Genetic Background: B10.Cg-Ptprc^a Cd79b^m1Ghost H2^a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal B cell differentiation ( J:157450 )

• fraction C' is virtually absent whereas fractions B and C exhibit relative accumulation unlike in wild-type mice

arrested B cell differentiation ( J:157450 )

• at the CD43+B220+ stage

absent B cells ( J:157450 )

• mice lack peripheral B cells unlike wild-type mice

decreased IgA level ( J:157450 )

• absent

decreased IgG level ( J:157450 )

• absent

absent Peyer's patches ( J:157450 )

hematopoietic system

abnormal B cell differentiation ( J:157450 )

• fraction C' is virtually absent whereas fractions B and C exhibit relative accumulation unlike in wild-type mice

arrested B cell differentiation ( J:157450 )

• at the CD43+B220+ stage

absent B cells ( J:157450 )

• mice lack peripheral B cells unlike wild-type mice

decreased IgA level ( J:157450 )

• absent

decreased IgG level ( J:157450 )

• absent