Phenotypes Associated with This Genotype

Genotype
MGI:4430566

• Allelic Composition: Fasl^gld/Fasl^gld
• Genetic Background: involves: C3H/HeJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

enlarged spleen ( J:171440 )

increased spleen weight ( J:171440 )

abnormal osteoclast physiology ( J:156947 )

• 17beta-estradiol, dihydrotestosterone, and pyrazole all fail to stimulate osteoclast apoptosis in culture

enlarged lymph nodes ( J:171440 )

skeleton

abnormal osteoclast physiology ( J:156947 )

• 17beta-estradiol, dihydrotestosterone, and pyrazole all fail to stimulate osteoclast apoptosis in culture

hematopoietic system

enlarged spleen ( J:171440 )

increased spleen weight ( J:171440 )

abnormal osteoclast physiology ( J:156947 )

• 17beta-estradiol, dihydrotestosterone, and pyrazole all fail to stimulate osteoclast apoptosis in culture

growth/size/body

enlarged spleen ( J:171440 )

increased spleen weight ( J:171440 )