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Phenotypes Associated with This Genotype
Genotype
MGI:4420975
Allelic
Composition		 Ptentm1Hwu/Pten+
Tg(Pbsn-cre)4Prb/0
Genetic
Background		 involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Hwu mutation (17 available); any Pten mutation (87 available)
Tg(Pbsn-cre)4Prb mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased prostate intraepithelial neoplasia incidence ( J:93902 )
• latency to prostate intraepithelial neoplasia is 8 to 10 months

endocrine/exocrine glands
increased prostate intraepithelial neoplasia incidence ( J:93902 )
• latency to prostate intraepithelial neoplasia is 8 to 10 months

reproductive system
increased prostate intraepithelial neoplasia incidence ( J:93902 )
• latency to prostate intraepithelial neoplasia is 8 to 10 months

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory