Mouse Genome Informatics
cn
    Ehmt1tm1.1Tara/Ehmt1tm1.1Tara
Tg(Camk2a-cre)2Gsc/0

involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• the specific neuronal cell architecture in the striatum and the hippocampus is not altered

behavior/neurological
• almost completely lack a preference for sucrose
• almost completely lack a preference for sucrose
• make more entries into and spend more time in open arms in an elevated plus maze
• starting around 6-8 weeks of age in an open field make fewer total arm entries in an elevated plus maze
• do not remember their negative experience
• do not remember their negative experience
• slightly improved performance in some trials during standard accelerated rotarod analysis
• in a new environment
• in a new environment

growth/size/body
• almost double the body weight as compared to controls by 5-6 months of age

Mouse Models of Human Disease
OMIM IDRef(s)
Kleefstra Syndrome 610253 J:155739