About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4418566
Allelic
Composition
Ehmt1tm1.1Tara/Ehmt1tm1.1Tara
Tg(Camk2a-cre)2Gsc/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ehmt1tm1.1Tara mutation (0 available); any Ehmt1 mutation (39 available)
Tg(Camk2a-cre)2Gsc mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• the specific neuronal cell architecture in the striatum and the hippocampus is not altered (J:155739)
• the specific neuronal cell architecture in the striatum and the hippocampus is not altered (J:155739)

behavior/neurological
• almost completely lack a preference for sucrose (J:155739)
• almost completely lack a preference for sucrose (J:155739)
• almost completely lack a preference for sucrose (J:155739)
• almost completely lack a preference for sucrose (J:155739)
• make more entries into and spend more time in open arms in an elevated plus maze (J:155739)
• make more entries into and spend more time in open arms in an elevated plus maze (J:155739)
• starting around 6-8 weeks of age in an open field make fewer total arm entries in an elevated plus maze (J:155739)
• starting around 6-8 weeks of age in an open field make fewer total arm entries in an elevated plus maze (J:155739)
• do not remember their negative experience (J:155739)
• do not remember their negative experience (J:155739)
• do not remember their negative experience (J:155739)
• do not remember their negative experience (J:155739)
• slightly improved performance in some trials during standard accelerated rotarod analysis (J:155739)
• slightly improved performance in some trials during standard accelerated rotarod analysis (J:155739)
• in a new environment (J:155739)
• in a new environment (J:155739)
• in a new environment (J:155739)
• in a new environment (J:155739)

growth/size/body
• almost double the body weight as compared to controls by 5-6 months of age (J:155739)
• almost double the body weight as compared to controls by 5-6 months of age (J:155739)

Mouse Models of Human Disease
OMIM ID Ref(s)
Kleefstra Syndrome 610253 J:155739


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/26/2016
MGI 6.02
The Jackson Laboratory