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Phenotypes Associated with This Genotype
Genotype
MGI:4418053
Allelic
Composition		 Tbx2tm1.1(cre)Vmc/Tbx2+
Tbx3tm1.1(cre)Vmc/Tbx3+
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbx2tm1.1(cre)Vmc mutation (0 available); any Tbx2 mutation (29 available)
Tbx3tm1.1(cre)Vmc mutation (0 available); any Tbx3 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
cleft secondary palate ( J:154920 )
• 5 of 13 embryos show complete cleft palate at E18.5

digestive/alimentary system
cleft secondary palate ( J:154920 )
• 5 of 13 embryos show complete cleft palate at E18.5

growth/size/body
cleft secondary palate ( J:154920 )
• 5 of 13 embryos show complete cleft palate at E18.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory