Phenotypes Associated with This Genotype

Genotype
MGI:4415789

• Allelic Composition: Mapk12^tm1Lex/Mapk12^tm1Lex; Tg(Myog-cre)1Eno/0
• Genetic Background: involves: 129S/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased angiogenesis ( J:155408 )

• marker expression indicates that exercise-induced angiogenesis is decreased compared to in similarly treated wild-type mice

cellular

decreased mitochondrial fission ( J:155408 )

• marker expression indicates that exercise-induced mitochondrial biogenesis is decreased compared to in similarly treated wild-type mice

muscle

muscle phenotype ( J:155408 )

N • mice exhibit normal fiber-type transformation in response to endurance exercise