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Phenotypes Associated with This Genotype
Genotype
MGI:4411984
Allelic
Composition		 Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stk4Gt(AJ0315)Wtsi mutation (0 available); any Stk4 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased histiocytic sarcoma incidence ( J:153945 )
• 2 out of 23 mice develop lethal histiocytic sarcomas over a period of 18-24 months

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory