Phenotypes for Chd7 Tg(Tbx1-cre)1Joe MGI:4410360 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Chd7^Gt(XK403)Byg/Chd7⁺ Tg(Tbx1-cre)1Joe/0
Genetic Background	either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CD-1)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd7^Gt(XK403)Byg mutation (0 available); any Chd7 mutation (134 available)
Tg(Tbx1-cre)1Joe mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Effects of Cre-mediated rescue of Chd7^Gt(XK403)Byg mutation on the arch artery phenotype at E10.5

cardiovascular system

abnormal fourth pharyngeal arch artery morphology ( J:154590 )

• in all mice

abnormal sixth pharyngeal arch artery morphology ( J:154590 )

• in 17% of mice

craniofacial

abnormal fourth pharyngeal arch artery morphology ( J:154590 )

• in all mice

abnormal sixth pharyngeal arch artery morphology ( J:154590 )

• in 17% of mice

embryo

abnormal fourth pharyngeal arch artery morphology ( J:154590 )

• in all mice

abnormal sixth pharyngeal arch artery morphology ( J:154590 )

• in 17% of mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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