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Phenotypes Associated with This Genotype
Genotype
MGI:4367224
Allelic
Composition		 Apoetm1Unc/Apoetm1Unc
Ldlrtm1Her/Ldlrtm1Her
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (35 available); any Apoe mutation (164 available)
Ldlrtm1Her mutation (21 available); any Ldlr mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased circulating cholesterol level ( J:59491 )
• plasma cholesterol on a high fat diet reaches 4120 mg/dl
• triglyceride levels are unaffected by diet

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory