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Phenotypes Associated with This Genotype
Genotype
MGI:4367211
Allelic
Composition		 Alox15tm1Fun/Alox15tm1Fun
Ldlrtm1Her/Ldlrtm1Her
Genetic
Background		 involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Alox15tm1Fun mutation (3 available); any Alox15 mutation (45 available)
Ldlrtm1Her mutation (21 available); any Ldlr mutation (79 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased susceptibility to atherosclerosis ( J:86385 )
• reduced atherosclerotic lesions when fed a high fat diet for 3 or 9 weeks

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory