Analysis Tools
cardiovascular system
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• pronounced reduction in atherosclerotic plaques after 12 and 24 weeks on a high fat diet
• 50% reduction in plaque area in the descending aorta at 12 weeks
• 60% reduction in plaque area in the descending aorta at 24 weeks
• total collagen and elastin in plaques is elevated at 12 weeks
• total collagen and elastin in plaques is at control levels at 24 weeks
• increased synthesis and decreased degradation of collagen and elastin at 12 weeks
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hematopoietic system
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• few macrophage in plaques at 12 weeks
• macrophage numbers in plaques similar to controls at 24 weeks
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immune system
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• few macrophage in plaques at 12 weeks
• macrophage numbers in plaques similar to controls at 24 weeks
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