Phenotypes for Ctnnb1 Tg(Cryaa-cre)10Mlr MGI:4366459 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm1Mmt/Ctnnb1^tm1Mmt Tg(Cryaa-cre)10Mlr/0
Genetic Background	involves: 129X1/SvJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm1Mmt mutation (0 available); any Ctnnb1 mutation (49 available)
Tg(Cryaa-cre)10Mlr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

increased lens epithelium apoptosis ( J:152850 )

abnormal lens epithelium morphology ( J:152850 )

• at E15.5, lens epithelial cells accumulate posterior to the lens equator unlike in wild-type mice

• lens epithelial cells fail to exhibit the cell cycle

microphthalmia ( J:152850 )

cellular

increased lens epithelium apoptosis ( J:152850 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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