Mouse Genome Informatics
ot
    Fmr1tm1Cgr/Y
involves: 129P2/OlaHsd * C57BL/6J
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mutants exhibit more exploratory behavior than controls, displaying more line crossings in the lit compartment
• mutants do not seem to be impaired in the retrieval of spatial and nonspatial information in training and reversal trials once this information has been learned, but they are impaired in their acquisition of the reversal task
• mutants show significantly more crossings through three infrared beams in an empty cage over 40 min

endocrine/exocrine glands
• macroorchidism develops over time
• weight of testis increases over time, however no structural abnormalities are observed

reproductive system
• macroorchidism develops over time
• weight of testis increases over time, however no structural abnormalities are observed

Mouse Models of Human Disease
OMIM IDRef(s)
Fragile X Mental Retardation Syndrome 300624 J:19220