Phenotypes for Hr Tg(KRT14-Ptgs2)1Sumf MGI:4366350 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hr^hr/Hr^hr Tg(KRT14-Ptgs2)1Sumf/0
Genetic Background	involves: C57BL/6 * DBA/2 * FVB/N * SKH1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hr^hr mutation (18 available); any Hr mutation (89 available)
Tg(KRT14-Ptgs2)1Sumf mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased incidence of tumors by UV-induction ( J:121635 )

homeostasis/metabolism

increased prostaglandin level ( J:121635 )

• in the epidermis

increased incidence of tumors by UV-induction ( J:121635 )

cellular

decreased cell proliferation ( J:121635 )

• slightly in the skin of UV-exposed mice compared to skin from similarly treated wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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