Phenotypes Associated with This Genotype

Genotype
MGI:4361837

• Allelic Composition: Fas^lpr/Fas^lpr
• Genetic Background: involves: C57BL/6 * MRL/Mp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

enlarged spleen ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgA level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG1 level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG2a level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG2b level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG3 level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgM level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

lymph node hyperplasia ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased anti-double stranded DNA antibody level ( J:73396 )

• at day 275

increased anti-single stranded DNA antibody level ( J:73396 )

• at day 275

hematopoietic system

enlarged spleen ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgA level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG1 level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG2a level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG2b level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgG3 level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

increased IgM level ( J:73396 )

• at day 175 and 275 compared with wild-type mice

growth/size/body

enlarged spleen ( J:73396 )

• at day 175 and 275 compared with wild-type mice