Phenotypes for Edil3 Gt(ROSA)26Sor Wnk1 MGI:4360982 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(Wnk1)Clhu}/Gt(ROSA)26Sor⁺ Wnk1^{Gt(OST38262)Lex}/Wnk1^{Gt(OST38262)Lex} Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3^{Tg(Sox2-cre)1Amc} mutation (5 available); any Edil3 mutation (42 available)
Gt(ROSA)26Sor^{tm1(Wnk1)Clhu} mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
Wnk1^{Gt(OST38262)Lex} mutation (1 available); any Wnk1 mutation (113 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis ( J:152906 )

• expression of Wnk1 in the somatic embryonic cells fails to rescue the phenotypes seen in Wnk1 null embryos

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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