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Phenotypes Associated with This Genotype
Genotype
MGI:4360981
Allelic
Composition		 Gt(ROSA)26Sortm1(Wnk1)Clhu/Gt(ROSA)26Sor+
Kdrtm1(cre)Sato/Kdr+
Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex
Genetic
Background		 involves: 129S1/Sv * 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Wnk1)Clhu mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
Kdrtm1(cre)Sato mutation (1 available); any Kdr mutation (71 available)
Wnk1Gt(OST38262)Lex mutation (1 available); any Wnk1 mutation (113 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:152906 )
N
• unlike single Wnk1 homozygotes, heart morphology is grossly normal

embryo
abnormal embryo development ( J:152906 )
• the incidence of abnormal embryos is increased compared to controls indicating only a partial rescue

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory