Phenotypes for Brca1 Cdkn1a MGI:4360342 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Brca1^tm2.1Cxd/Brca1^tm2.1Cxd Cdkn1a^tm1Led/Cdkn1a^tm1Led
Genetic Background	involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Brca1^tm2.1Cxd mutation (1 available); any Brca1 mutation (113 available)
Cdkn1a^tm1Led mutation (1 available); any Cdkn1a mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:81559 )

• improved embryonic survival

• death within 24 hours of birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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