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Phenotypes Associated with This Genotype
Genotype
MGI:4358774
Allelic
Composition		 ApcMin/Apc+
Pla2g4atm1Jvb/Pla2g4atm1Jvb
Genetic
Background		 B6.Cg-Pla2g4atm1Jvb ApcMin
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (151 available)
Pla2g4atm1Jvb mutation (0 available); any Pla2g4a mutation (63 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
intestine polyps ( J:68495 )
• mice exhibit a 83% reduction in small intestine polyp number with a 22% decrease in size compared with polyps in ApcMin heterozygotes
• mice exhibit the same number of polyps in the large intestine as in ApcMin heterozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory