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Phenotypes Associated with This Genotype
Genotype
MGI:4356289
Allelic
Composition
Tg(CD2-Ccdc86)1Hfuj/?
Genetic
Background
B6.FVB-Tg(CD2-Ccdc86)1Hfuj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CD2-Ccdc86)1Hfuj mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• CD4+ and CD8+ T cells have increased rates of activation induced cell death upon secondary stimulation
• T cells have increased expression of the Fas receptor

hematopoietic system
• CD4+ and CD8+ T cells have increased rates of activation induced cell death upon secondary stimulation
• T cells have increased expression of the Fas receptor

cellular
• CD4+ and CD8+ T cells have increased rates of activation induced cell death upon secondary stimulation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory