About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4356085
Allelic
Composition		 Etv6tm1(RUNX1)Haho/Etv6+
Runx1tm3Spe/Runx1tm3Spe
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv6tm1(RUNX1)Haho mutation (1 available); any Etv6 mutation (144 available)
Runx1tm3Spe mutation (0 available); any Runx1 mutation (34 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:151639 )
• all mice die within 8 days of treatment with pIpC unlike control mice

hematopoietic system
anemia ( J:151639 )
• severe following pIpC treatment
decreased hematopoietic stem cell number ( J:151639 )
• following pIpC treatment

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory