About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4355904
Allelic
Composition		 Prdm1tm2.1Nutt/Prdm1tm2.1Nutt
Tg(Lck-cre)1Cwi/?
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm1tm2.1Nutt mutation (2 available); any Prdm1 mutation (64 available)
Tg(Lck-cre)1Cwi mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Orthomyxoviridae infection ( J:151858 )
• mice have some delay in recovering from an influenza infection compared to controls
• mice show pronounced lymphocytic accumulation in the tertiary lymphoid tissue after influenza infection compared to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory