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Phenotypes Associated with This Genotype
Genotype
MGI:4354589
Allelic
Composition		 Itktm1Ljb/Itktm1Ljb
Tg(TcraTcrb)1100Mjb/?
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/10
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itktm1Ljb mutation (0 available); any Itk mutation (51 available)
Tg(TcraTcrb)1100Mjb mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:113408 )
N
• the altered CD8+ T cell development that generates a large proportion of memory T cells in Itktm1Ljb homozygotes does not occur in these mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory