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Phenotypes Associated with This Genotype
Genotype
MGI:3851922
Allelic
Composition
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(CAG-Otx2,-EGFP)1Eno/?
Genetic
Background
involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (26 available)
Tg(CAG-Otx2,-EGFP)1Eno mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some mice die within 4-6 hours after birth from brain hemorrhaging

cardiovascular system
• some mice die within 4-6 hours after birth from brain hemorrhaging
• hemorrhaging results from ossification defects in the skull

craniofacial
• ossification defects lead to the presence of soft tissues in the frontal and interparietal bone

nervous system
• some mice die within 4-6 hours after birth from brain hemorrhaging
• hemorrhaging results from ossification defects in the skull

skeleton
• ossification defects lead to the presence of soft tissues in the frontal and interparietal bone
• ossification defects lead to the presence of soft tissues in the frontal and interparietal bone and incomplete skull closure


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory