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Phenotypes Associated with This Genotype
Genotype
MGI:3851590
Allelic
Composition		 Shc1tm1Ravi/Shc1tm1Ravi
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shc1tm1Ravi mutation (1 available); any Shc1 mutation (66 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:111058 )
• body weight is less than controls at 25 days of age

nervous system
decreased brain size ( J:111058 )
• brain weight is less than controls at 25 days of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory