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Phenotypes Associated with This Genotype
Genotype
MGI:3850555
Allelic
Composition		 Il4tm1Nnt/Il4tm1Nnt
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il4tm1Nnt mutation (1 available); any Il4 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal interleukin-4 secretion ( J:91403 )
• lymphocytes fail to produce IL-4
decreased susceptibility to autoimmune disorder ( J:91403 )
• some mice have a less severe degree of airway hyperresponsiveness after sensitization and challenge with OVA peptide

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory