Phenotypes Associated with This Genotype

Genotype
MGI:3850531

• Allelic Composition: Apobec1^tm1Rub/Apobec1^tm1Rub; Apoe^{tm1(APOE*2)Mae}/Apoe^{tm1(APOE*2)Mae}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:79196 )

• 60% in males compared to in Apoe^{tm1(APOE*2)Mae} homozygotes

decreased circulating cholesterol level ( J:79196 )

• 18% in female mice compared to in Apoe^{tm1(APOE*2)Mae} homozygotes

decreased circulating LDL cholesterol level ( J:79196 )

• in male and female mice compared to in Apoe^{tm1(APOE*2)Mae} homozygotes

increased circulating triglyceride level ( J:79196 )

• female and male mice exhibit increased serum triglyceride levels (60% and 100%) compared to in Apoe^{tm1(APOE*2)Mae} homozygotes

increased circulating VLDL triglyceride level ( J:79196 )

• compared to in Apoe^{tm1(APOE*2)Mae} homozygotes