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Phenotypes Associated with This Genotype
Genotype
MGI:3850077
Allelic
Composition
Neurog3tm1(Neurog3,cre/ERT)Ggu/Neurog3tm1.1(cre/ERT)Ggu
Tg(Pdx1-cre/Esr1*)1Mga/0
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Neurog3tm1.1(cre/ERT)Ggu mutation (0 available); any Neurog3 mutation (18 available)
Neurog3tm1(Neurog3,cre/ERT)Ggu mutation (0 available); any Neurog3 mutation (18 available)
Tg(Pdx1-cre/Esr1*)1Mga mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in male mice 4 weeks after tamoxifen treatment
• in male mice 12 weeks after tamoxifen treatment
• 12 weeks after tamoxifen treatment, postglucose-challenge-serum-insulin levels are decreased unlike in similarly treated wild-type mice
• in female mice 2 and 3 months after tamoxifen treatment and in male mice 12 weeks after tamoxifen treatment


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory